Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EIF4EBP1 All Species: 20
Human Site: T37 Identified Species: 44
UniProt: Q13541 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13541 NP_004086.1 118 12580 T37 P P G D Y S T T P G G T L F S
Chimpanzee Pan troglodytes XP_001136348 133 14823 G50 Y C T T Q G C G G G G A L F S
Rhesus Macaque Macaca mulatta XP_001091933 141 14878 T37 P P G D Y S T T P G G T L F S
Dog Lupus familis XP_549448 118 12523 T37 P P G D Y S T T P G G T L F S
Cat Felis silvestris
Mouse Mus musculus Q60876 117 12306 T36 P P G D Y S T T P G G T L F S
Rat Rattus norvegicus Q62622 117 12385 T36 P P G D Y S T T P G G T L F S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514570 67 7606
Chicken Gallus gallus XP_424384 116 12481 S36 P L P P G D Y S T T P G G T V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q98TT6 112 12513 Q32 Q L P D C Y S Q T P G G T L F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001120078 115 12648 S35 Q L P N D Y S S T P G G T L F
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_001077103 113 12005 D32 D P S Q L P H D Y S T T P G G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 46.6 75.8 94.9 N.A. 90.6 92.3 N.A. 44.9 66 N.A. 56.7 N.A. N.A. 47.4 N.A. 52.5
Protein Similarity: 100 59.4 80.1 97.4 N.A. 94 95.7 N.A. 49.1 76.2 N.A. 67.8 N.A. N.A. 65.2 N.A. 66.1
P-Site Identity: 100 33.3 100 100 N.A. 100 100 N.A. 0 6.6 N.A. 13.3 N.A. N.A. 6.6 N.A. 13.3
P-Site Similarity: 100 33.3 100 100 N.A. 100 100 N.A. 0 13.3 N.A. 20 N.A. N.A. 26.6 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % A
% Cys: 0 10 0 0 10 0 10 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 55 10 10 0 10 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 55 19 % F
% Gly: 0 0 46 0 10 10 0 10 10 55 73 28 10 10 10 % G
% His: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 28 0 0 10 0 0 0 0 0 0 0 55 19 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 55 55 28 10 0 10 0 0 46 19 10 0 10 0 0 % P
% Gln: 19 0 0 10 10 0 0 10 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 10 0 0 46 19 19 0 10 0 0 0 0 55 % S
% Thr: 0 0 10 10 0 0 46 46 28 10 10 55 19 10 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 0 46 19 10 0 10 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _